uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A comparative study of the bioactivnity of three materials for dental applications
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.
Show others and affiliations
2008 (English)In: Dental Materials, ISSN 0109-5641, E-ISSN 1879-0097, Vol. 24, no 5, 653-659 p.Article in journal (Refereed) Published
Abstract [en]

Objectives. The aim of this work was to investigate the in vitro bioactivity of two different experimental dental luting cement formulations based on calcium aluminate (CA) in comparison with glass ionomer cement (GIC). One of the CA-based formulations was a hybrid between CA and GIC. Methods. Samples were submerged in phosphate buffered saline and stored at 37 degrees C for four periods of time: 1 h, 1 day, 7 days and 4 weeks. After storage the samples were analyzed in order to investigate if a surface layer of hydroxyapatite had formed. The analysis techniques used included grazing incidence X-ray diffraction, scanning electron microscopy, energy dispersive spectroscopy and transmission electron microscopy. Results. Both the CA-containing formulations were found to be bioactive. The highest degree of bioactivity was found on the sample with only CA as active substance. A relatively thick and totally covering layer was already formed after 24 h. On the hybrid material hydroxyapatite was found after 7 days. The GIC showed no bioactivity during the test period. Significance. The utilization of a bioactive material for tooth restorations will give an opportunity for remineralization and a natural and durable seal of the tooth-material interface. Materials based on CA exhibit bioactivity.

Place, publisher, year, edition, pages
2008. Vol. 24, no 5, 653-659 p.
Keyword [en]
bioactivity, calcium aluminate, glass ionomer, hydroxyapatite, surface characterization, transmission electron microscopy, x-ray diffraction, scanning electron microscopy, simulated body fluid
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:uu:diva-152143DOI: 10.1016/j.dental.2007.06.028ISI: 000255735100013OAI: oai:DiVA.org:uu-152143DiVA: diva2:412532
Available from: 2011-04-25 Created: 2011-04-25 Last updated: 2017-12-11Bibliographically approved
In thesis
1. Calcium-Aluminate as Biomaterial: Synthesis, Design and Evaluation
Open this publication in new window or tab >>Calcium-Aluminate as Biomaterial: Synthesis, Design and Evaluation
2008 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

In this thesis different aspects of calcium-aluminate (CA) as biomaterial are presented. Calcium aluminate is a chemically bonded ceramic with inherent properties making it suitable for use as biomaterial in some applications. In this thesis the emphasis is put on the basic chemical, physical and mechanical properties that may be achieved using the CA system as well as synthesis of the CA raw material. The basis for using CA in any application is the synthesis of the raw material. Different synthesis routes for producing CA are presented with focus on high temperature routes and the micro-structural and phase development during synthesis. As a base for further understanding of the CA properties a thorough outline of the reaction chemistry for CA is presented also including a description of how the reactions may be controlled and how formulations can be designed. The surface reactions of CA when subjected to simulated body fluid showed that CA is in vitro bioactive. An in vivo study in teeth also indicates that CA produces apatite at the tooth material interface. Dental materials are subjected to a harsh environment in the mouth with high mechanical forces, erosion and thermal changes. Also the demands on precise handling characteristics are high. For these reasons the in vitro evaluation of physical and mechanical properties are important. In this work several mechanical and physical properties of Ca-based formulations for dental applications has been tested using different methods. Some attention is also put on the specific characteristics of CA and the difficulties that arise when new material classes needs to be tested according to consensus standard methods. Finally studies on a CA-based formulation intended for Vertebroplasty is presented. The studies include basic mechanical properties as well as testing the material in an in vitro model utilising synthetic cancellous bone.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2008. 87 p.
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214 ; 452
Keyword
Calcium-aluminate, Biomaterial, Dental materials, Vertebroplasty, Chemically Bonded Ceramics, Synthesis
National Category
Biomaterials Science
Identifiers
urn:nbn:se:uu:diva-9173 (URN)978-91-554-7248-1 (ISBN)
Public defence
2008-09-12, Siegbahnsalen, Ångströmlaboratoriet, Lägerhyddsvägen 1, Uppsala, 10:15
Opponent
Supervisors
Available from: 2008-08-19 Created: 2008-08-19 Last updated: 2011-07-08Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Svahn, FredrikEngqvist, Håkan

Search in DiVA

By author/editor
Svahn, FredrikEngqvist, Håkan
By organisation
Applied Materials Sciences
In the same journal
Dental Materials
Engineering and Technology

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 821 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf