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Impact of Time in the Development of Acute Appendicitis
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences.
2008 (English)In: Digestive Surgery, ISSN 0253-4886, E-ISSN 1421-9883, Vol. 25, no 5, 394-399 p.Article in journal (Refereed) Published
Abstract [en]

Background: The aim of this study was to elucidate the natural history of appendicitis. Methods: Data was collected prospectively from consecutive patients admitted to hospital for acute abdominal pain. The degree of appendiceal inflammation in relation to preoperative duration of pain was analysed. Results: The study comprised 253 patients operated on for acute appendicitis that could recall the onset of abdominal pain. There was a longer duration of pre-hospital pain in patients, irrespective of age, with perforated appendicitis compared to patients with phlegmonous or gangrenous appendicitis (p < 0.001). In the multivariate analysis, patient age and preoperative duration of pain were independent risk factors for perforation. Conclusion: Patient delay in presentation is the predominant factor determining the incidence of complicated appendicitis, and this delay is not influenced by age or gender.

Place, publisher, year, edition, pages
2008. Vol. 25, no 5, 394-399 p.
Keyword [en]
Acute abdominal pain, Acute appendicitis, diagnosis, Appendicitis, natural history
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-152250DOI: 10.1159/000180451ISI: 000261525300017PubMedID: 19065056OAI: oai:DiVA.org:uu-152250DiVA: diva2:413068
Available from: 2011-04-27 Created: 2011-04-27 Last updated: 2011-04-27Bibliographically approved

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