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Mass spectrometry of proteins - Uppsala perspectives on past and present: Paper in honor of Prof. Peter Roepstorff's 65th birthday
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Physical and Analytical Chemistry, Analytical Chemistry.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Ion Physics.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Ion Physics.
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology.
2007 (English)In: International Journal of Mass Spectrometry, ISSN 1387-3806, E-ISSN 1873-2798, Vol. 268, no 2-3, 73-82 p.Article in journal (Refereed) Published
Abstract [en]

The development of biological mass spectrometry has been rapid in the past three to four decades. In particular, the possibility to detect and identify peptides and proteins from biologically and medically relevant samples has revolutionized life sciences. The development has gone from a stage where the detection of insulin in a mass spectrum was a major event to one in which the recording of mass spectra with more than 104 resolved and calibrating peaks in each spectrum is a routine task.

In this paper, the evolution of protein mass spectrometry will be discussed from the Uppsala horizon with special emphasis on the unique coupling between ion induced desorption of biomolecules and ion track physics.

Place, publisher, year, edition, pages
2007. Vol. 268, no 2-3, 73-82 p.
Keyword [en]
Mass spectrometry, Plasma desorption, Liquid chromatography, Fourier transform, Protein
National Category
Natural Sciences Engineering and Technology
Identifiers
URN: urn:nbn:se:uu:diva-13643DOI: 10.1016/j.ijms.2007.06.011ISI: 000251467500002OAI: oai:DiVA.org:uu-13643DiVA: diva2:41413
Available from: 2008-01-31 Created: 2008-01-31 Last updated: 2017-12-11Bibliographically approved

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Bergquist, JonasHåkansson, PerSundqvist, BoZubarev, Roman

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