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Evaluation of electrogustometry and the filter paper disc method for taste assessment
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland.ORCID iD: 0000-0003-3691-8326
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland.
2011 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, E-ISSN 1651-2251, Vol. 131, no 5, 488-493 p.Article in journal (Refereed) Published
Description
Abstract [en]

Conclusion:

The results indicate that electrogustometry and the filter paper disc method are reliable methods to measure taste with a high degree of reproducibility.

Objectives:

To thoroughly evaluate the reliability of electrogustometry and the filter paper disc method for taste assessments.

Methods:

Thirty-nine healthy test persons without any history of chronic middle ear disease, aged between 27 and 62 years, were recruited. In all, 772 electrogustometry and 30 filter paper disc assessments were made. A nerve decay test was performed, with measures taken before and after eating sweet, sour, bitter, salt, a mild or spicy meal, after smoking, and after taking Swedish tobacco snuff ('snus'), as well as before and after local anesthesia of the tongue. Measurements were performed on 5 consecutive days and repeatedly during 1 day. The correlation between electrogustometry and the filter paper disc method was also studied.

Results:

The results indicate that electrogustometry and the filter paper disc method are reliable methods to measure taste with a high degree of reproducibility. The only actions causing significant changes in the electrogustometry readings were eating bitter a substance and having local anesthesia of the tongue. The correlation between the methods was statistically significant except for the bitter flavor, where the correlation was just below the level of significance.

Place, publisher, year, edition, pages
2011. Vol. 131, no 5, 488-493 p.
Keyword [en]
Chorda tympani, ear disease, ear surgery
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-152942DOI: 10.3109/00016489.2010.535850ISI: 000289562600005PubMedID: 21391775OAI: oai:DiVA.org:uu-152942DiVA: diva2:414514
Available from: 2011-05-03 Created: 2011-05-03 Last updated: 2017-12-11Bibliographically approved
In thesis
1. The Chorda Tympani Nerve: Role in Taste Impairment in Middle Ear Disease and after Ear Surgery
Open this publication in new window or tab >>The Chorda Tympani Nerve: Role in Taste Impairment in Middle Ear Disease and after Ear Surgery
2017 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The chorda tympani nerve, also known as the taste nerve, runs uncovered through the middle ear cavity, a localization that exposes the nerve to pathological processes and surgical trauma in the middle ear. People operated on for otosclerosis tend to complain more about postoperative taste disturbances than those operated on for chronic otitis media. It has been suggested that this difference may be explained by gradual deterioration of chorda tympani nerve function caused by chronic otitis media infection and that further impairment caused by surgery is less noticeable in these patients.

This thesis aimed to evaluate the function of the chorda tympani nerve, the effects of middle ear disease on taste and complications resulting from ear surgery for chronic otitis media or otosclerosis. This information will help to improve the ear surgeon’s ability to predict the prognosis of iatrogenic taste disturbances in patients with middle ear disease and after ear surgery.

Taste was assessed using electrogustometry and the filter paper disc method before and after surgery for chronic otitis media or otosclerosis. Patients also completed questionnaires about symptoms and quality of life. The status of the chorda tympani nerve upon surgical opening of the ear and grading of the trauma to the nerve during the surgery were recorded. The ultrastructure of the chorda tympani nerve from healthy ears and from ears with chronic otitis media was examined. Electrogustometry and the filter paper disc method were evaluated.

The results of electrogustometry and the filter paper disc method were highly reproducible, although their correlation was moderate. Patients with chronic otitis media, patients with a more traumatized nerve, female patients and younger patients were more likely to report postoperative taste disturbances. Most of the patients recovered their taste after 1 year. The quality of life study showed only minor changes after surgery. Electron microscopic observations of nerves from ears with chronic otitis media showed signs of structural degeneration, although signs of regeneration, such as sprouting were also observed. This results may explain the recovery of taste postoperatively and indicate that the nerve should be carefully handled during surgery.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2017. 54 p.
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 1306
Keyword
Chorda tympani nerve, ear surgery, taste, chronic suppurative otitis media, otosclerosis, electrogustometry, filter paper disc method, quality of life, transmission electron microscopy, degeneration, sprouting
National Category
Medical and Health Sciences
Research subject
Surgery
Identifiers
urn:nbn:se:uu:diva-316591 (URN)978-91-554-9837-5 (ISBN)
Public defence
2017-04-27, Vårdskolans Aula, Ing 21, Västmanlands sjukhus Västerås, Västerås, 13:00 (Swedish)
Opponent
Supervisors
Available from: 2017-04-05 Created: 2017-03-07 Last updated: 2017-04-18

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Knutsson, JohanRosenblad, Andreas

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