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Prospective malignancy grading of invasive squamous carcinoma of the uterine cervix. Prognostic significance in a long-term follow-up
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
2007 (English)In: Anticancer Research, ISSN 0250-7005, Vol. 27, no 4C, 2829-2832 p.Article in journal (Refereed) Published
Abstract [en]

A multifactorial grading score (MGS) for invasive squamous cell carcinoma of the uterine cervix has demonstrated its capacity to predict survival in a 5-10 year perspective and metastasis frequencies, and is a valuable tool for treatment schedules. In this study it was shown that the power of prognosis is valid even up to 20 years. In this material from 619 cervical carcinoma patients the MGS scores turned out to remain as strong as earlier proven. Earlier studies have shown that MGS is superior to other mono- and multifactorial grading systems, histological differentiation into cell types, age, clinical stage, irradiation and DNA-analysis. Treatment of cervical squamous cell carcinoma is more specific today to meet the patients' need for instance to preserve fertility or to minimize operation and eventually radiotherapy. The MGS score is a strong prognostic tool in patients with cervical carcinoma.

Place, publisher, year, edition, pages
2007. Vol. 27, no 4C, 2829-2832 p.
Keyword [en]
Carcinoma, Prognosis, Uterine cervix
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-13797ISI: 000248546100040PubMedID: 17695455OAI: oai:DiVA.org:uu-13797DiVA: diva2:41567
Available from: 2008-01-25 Created: 2008-01-25 Last updated: 2011-01-24Bibliographically approved

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