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Pulmonary Nocardiosis with Brain Abscess in a Sensitized Kidney Transplant Recipient with a History of Repeated Graft Loss and HLA-Antibody Depletion Treatment: A case report
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Transplantation Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Transplantation Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Transplantation Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Infectious Diseases.
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2008 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 113, no 1, 111-116 p.Article in journal (Refereed) Published
Abstract [en]

Nocardiosis is an opportunistic infection with unfavourable prognosis and is predominantly seen in immunocompromised patients. We here present a kidney transplant recipient with a history of two early graft losses who subsequently developed Human Leukocyte Antigen (HLA)-antibodies and underwent a desensitization treatment with plasmapheresis and monoclonal anti-CD20 antibody application. However, 3 months after a third HLA-identical kidney transplantation he developed Nocardiosis with pulmonary and asymptomatic brain manifestation. The present case report exemplifies this opportunistic infection and gives an overview of the literature.

Place, publisher, year, edition, pages
2008. Vol. 113, no 1, 111-116 p.
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-13946DOI: 10.3109/2000-1967-212ISI: 000263415100010PubMedID: 18521805OAI: oai:DiVA.org:uu-13946DiVA: diva2:41716
Available from: 2008-01-28 Created: 2009-02-05 Last updated: 2017-12-11Bibliographically approved

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Biglarnia, Ali-RezaWadström, JonasTufveson, GunnarEriksson, Britt-Marie

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