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Gastric carcinoid in a patient infected with Helicobacter pylori: A new entity?
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
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2011 (English)In: World Journal of Gastroenterology, ISSN 1007-9327, E-ISSN 2219-2840, Vol. 17, no 25, 3066-3068 p.Article in journal (Refereed) Published
Abstract [en]

There are four types of gastric carcinoid tumors, classified according to their histology and malignant potential. Only a few cases of carcinoid tumors in patients infected with Helicobacter pylori (H. pylon) have been reported so far. We report a patient infected with H. pylori presenting with a small solitary gastric carcinoid tumor with very low proliferative rate and normal gastrin levels. The tumor was endoscopically removed and the patient received an eradication therapy against H. pylori. No signs of metastatic disease have been found so far during more than 3 year of follow-up. Infection with H. pylon may cause chronic gastritis with normal or elevated gastrin levels, leading to the development of gastric carcinoids by mechanisms unrelated to gastrin. Enterochromaffin-like cell tumors related to a chronic H. pylori infection may be considered as a distinct type of gastric carcinoid tumors.

Place, publisher, year, edition, pages
2011. Vol. 17, no 25, 3066-3068 p.
Keyword [en]
Gastric carcinoids, Gastrin, Gastritis, Helicobacter pylori
National Category
Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:uu:diva-156626DOI: 10.3748/wjg.v17.i25.3066ISI: 000292890800014OAI: oai:DiVA.org:uu-156626DiVA: diva2:432779
Available from: 2011-08-06 Created: 2011-08-04 Last updated: 2017-12-08Bibliographically approved

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