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Asthma treatment preference study: a conjoint analysis of preferred drug treatments
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology.
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2004 (English)In: Chest, ISSN 0012-3692, E-ISSN 1931-3543, Vol. 125, no 3, 916-923 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE:

Assessment of patient preferences for attributes of asthma treatments.

METHODS:

Two hundred ninety-eight patients (age range, 18 to 60 years) from 15 centers in Sweden completed a questionnaire concerning their asthma, and ranked 18 alternative treatments using conjoint analysis. Patients were receiving treatment with either inhaled corticosteroids (ICS) and short-acting bronchodilator (n = 123) or ICS and long-acting bronchodilator (separate inhalers, n = 87; combination inhaler, n = 88). Attributes analyzed were maintenance treatment, additional reliever, time to onset and duration of reliever, number of symptom-free days (SFDs) per month, and out-of-pocket cost per month.

RESULTS:

Conjoint analysis showed that the most important aspect of treatment was SFD. Forty percent of the patients had <or= 15 SFDs per month. Eighty-five percent of the patients preferred another treatment over their current treatment. Treatment preferences were heterogeneous, and in 78% were not covered by current treatment guidelines. A total of 148 patients (50%) preferred a combination inhaler to separate inhalers, and 233 patients (78%) preferred a reliever that is both rapid and long acting. The most preferred treatment was a combination inhaler for maintenance and reliever use. On average, the patients were willing to pay an additional 328 Swedish krona [36 US dollars] per month for the change to the preferred treatment.

CONCLUSION:

SFDs were the most important attribute in asthma treatment. Patients were willing to pay for a switch to their preferred treatment. The most favored treatments were a reliever therapy that is both rapid and long acting and a combination inhaler for both maintenance and as-needed use.

Place, publisher, year, edition, pages
2004. Vol. 125, no 3, 916-923 p.
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Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-156839DOI: 10.1378/chest.125.3.916PubMedID: 15006950OAI: oai:DiVA.org:uu-156839DiVA: diva2:433411
Available from: 2011-08-10 Created: 2011-08-10 Last updated: 2017-12-08Bibliographically approved

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Johansson, GunnarStällberg, Björn

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