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Obtaining snapshots of genetic variation using hemiclonal analysis
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Animal Ecology.
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Animal Ecology.
2011 (English)In: Trends in Ecology & Evolution, ISSN 0169-5347, E-ISSN 1872-8383, Vol. 26, no 7, 359-368 p.Article, review/survey (Refereed) Published
Abstract [en]

Hemiclones are naturally occurring or artificially produced individuals that share a single specific genetic haplotype. Natural hemiclones are produced via hybridization between two closely related species, whereas hemiclonal analysis in Drosophila is carried out in the laboratory via crosses with artificially created 'clone-generator' females with a specific genetic make-up. Hemiclonal analysis in Drosophila has been applied successfully to date to obtain measures of standing genetic variation for numerous traits. Here, we review the current hemiclonal literature and suggest future directions for hemiclonal research, including its application in molecular and genomic studies, and the adaptation of natural hemiclonal systems to carry out Drosophila-type studies of standing genetic variation.

Place, publisher, year, edition, pages
2011. Vol. 26, no 7, 359-368 p.
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:uu:diva-156830DOI: 10.1016/j.tree.2011.03.011ISI: 000292676400010OAI: oai:DiVA.org:uu-156830DiVA: diva2:433902
Available from: 2011-08-11 Created: 2011-08-09 Last updated: 2017-12-08Bibliographically approved

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