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Is there evidence for convergent evolution around human microsatellites?
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolution, Genomics and Systematics, Evolutionary Biology. (Molecular evolution)
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolution, Genomics and Systematics, Evolutionary Biology.ORCID iD: 0000-0003-2370-6025
2007 (English)In: Molecular biology and evolution, ISSN 0737-4038, E-ISSN 1537-1719, Vol. 24, no 5, 1097-1100 p.Article in journal (Refereed) Published
Abstract [en]

A study by Vowles and Amos (2004) identified atypical patterns of base composition around human microsatellites and argued that microsatellites generate mutational biases in their flanking regions. Here, we perform simulations of molecular evolution using a simple model that suggest similar patterns can be produced without any such biases in genome evolution.

Place, publisher, year, edition, pages
2007. Vol. 24, no 5, 1097-1100 p.
Keyword [en]
Convergent evolution, Genome evolution, Microsatellite, Mutation bias, Simulation
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:uu:diva-15693DOI: 10.1093/molbev/msm051ISI: 000246802400002PubMedID: 17350937OAI: oai:DiVA.org:uu-15693DiVA: diva2:43464
Available from: 2008-03-03 Created: 2008-03-03 Last updated: 2017-12-08

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Webster, Matthew T.

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