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Theoretical estimation of retinal oxygenation during retinal detachment
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Physiology. (Hedenstierna)
2007 (English)In: Computers in Biology and Medicine, ISSN 0010-4825, E-ISSN 1879-0534, Vol. 37, no 6, 890-896 p.Article in journal (Refereed) Published
Abstract [en]

The aim of the present work was to simulate the oxygenation of the whole retina during different degrees of retinal detachment. A differential equation describing the oxygenation of the whole retina, at different degrees of detachment, was set up and solved numerically. The results show that the choroid can supply the outer retina with a fairly large amount of oxygen as long as the detachment height is lower than about 1mm. This study thus supports the view that hyperoxia may well prove to be clinically beneficial.


Place, publisher, year, edition, pages
2007. Vol. 37, no 6, 890-896 p.
Keyword [en]
Detachment, Diffusion, Mathematical model, Oxygen, Retina
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-15761DOI: 10.1016/j.compbiomed.2006.09.005ISI: 000246954900016PubMedID: 17055472OAI: oai:DiVA.org:uu-15761DiVA: diva2:43532
Available from: 2008-06-04 Created: 2008-06-04 Last updated: 2011-01-28Bibliographically approved

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