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Coronary Intervention Improves Disease Specific Health-Related Quality of Life but Not Individualised Quality of Life: A Potential Response Shift Effect?
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2011 (English)In: Applied Research in Quality of Life, ISSN 1871-2584, Vol. 6, no 1, 81-90 p.Article in journal (Refereed) Published
Abstract [en]

To explore potential response shift effects with different quality of life (QoL) instruments in cardiac patients undergoing coronary intervention. Study Design and Setting: Recalibration was assessed with the disease specific health-related quality of life (HRQL) instrument MacNew in combination with a then-test approach. Reconceptualisation and reprioritisation were assessed with the individualised QoL instrument SEIQoL-DW. Significant treatment effects were seen on the MacNew (global Delta: 0.6 +/- 1.1, p = 0.004) but not on the SEIQoL-DW (Delta: 3.3 +/- 16, p = 0.37) 6 months after coronary intervention. No recalibration effect was found on the MacNew then-test, while with the SEIQOL-DW potential response shift effects of reconceptualisation and reprioritisation were seen. For the first time response shift effects were explored in cardiac patients undergoing coronary intervention. This study confirmed that there is a clinically significant improvement in disease specific HRQL over time following successful coronary interventions. However, no treatment effect was seen for individualised QoL with the SEIQoL-DW. This might be due to reconceptualisation and reprioritisation response effects. Future studies need to focus on exploring response shift effects, and the interrelationship between its different components, captured by different patient reported outcome instruments in larger patient groups undergoing coronary interventions.

Place, publisher, year, edition, pages
2011. Vol. 6, no 1, 81-90 p.
Keyword [en]
Schedule for the evaluation of individualised quality of life - Direct weighting (SEIQoL-DW), MacNew, Heart disease, Angina, Coronary intervention, Response shift, Then-test
National Category
Pharmaceutical Sciences
URN: urn:nbn:se:uu:diva-158192DOI: 10.1007/s11482-010-9117-3ISI: 000293658500006OAI: oai:DiVA.org:uu-158192DiVA: diva2:438115
Available from: 2011-09-01 Created: 2011-09-01 Last updated: 2011-09-01Bibliographically approved

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