uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Cardiogenic oscillations in spontaneous breathing airway signal reflect respiratory system mechanics
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
Show others and affiliations
2011 (English)In: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 55, no 8, 980-986 p.Article in journal (Refereed) Published
Abstract [en]

Background: Heartbeat-related pressure oscillations appear at the airway opening. We investigated whether these cardiogenic oscillations (COS) - extracted from spontaneous breathing signals - reflect the compliance of the respiratory system. Methods: Fifteen volunteers breathed spontaneously at normal or reduced chest wall compliance, i.e. with and without thorax strapping, and at normal or reduced lung compliance, induced by positive end-expiratory pressure (PEEP). COS-related signals were extracted by averaging the flow and pressure curve sections, temporally aligned to the electrocardiogram signal. Results: COS-related airway pressure and flow curves correlated closely for each subject (r(2) =0.97±0.02, P<0.0001). At the unstrapped thorax, the oscillation's amplitudes were 0.07±0.03 cmH(2) O (pressure) and 22±10 ml/s (flow). COS-related pressure amplitudes correlated closely with the ratio of tidal volume divided by pressure amplitude (r(2) =0.88, P<0.001) and furthermore increased with either thorax strapping (P<0.001) or with increasing PEEP (P=0.049). Conclusion: We conclude that COS extracted from the pressure and flow signal reflect the compliance of the respiratory system and could potentially allow estimating respiratory system mechanics during spontaneous breathing.

Place, publisher, year, edition, pages
2011. Vol. 55, no 8, 980-986 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-158404DOI: 10.1111/j.1399-6576.2011.02488.xPubMedID: 21770903OAI: oai:DiVA.org:uu-158404DiVA: diva2:439313
Available from: 2011-09-07 Created: 2011-09-07 Last updated: 2017-12-08Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Authority records BETA

Lichtwarck-Aschoff, Michael

Search in DiVA

By author/editor
Lichtwarck-Aschoff, Michael
By organisation
Anaesthesiology and Intensive Care
In the same journal
Acta Anaesthesiologica Scandinavica
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 371 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf