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Toward a Definition of Sarcopenia
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences.
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2011 (English)In: Clinics in Geriatric Medicine, ISSN 0749-0690, Vol. 27, no 3, 341-353 p.Article in journal (Refereed) Published
Abstract [en]

The definition of sarcopenia has been thoroughly discussed by scientific stakeholders and industry representatives to increase the clinical applicability of the concept. The pooled consensus from 3 of 5 recent and parallel processes, of which 2 are pending, is that sarcopenia is mainly, but not only, an age-related condition defined by the combined presence of reduced muscle mass and muscle function. Contributing factors to sarcopenia are senescence, chronic disease, physical inactivity, and poor food intake. Cachexia may be considered as one etiologic pathway of an accelerated sarcopenia. The adjusted and extended definitions of sarcopenia promote the clinical use of the concept.

Place, publisher, year, edition, pages
2011. Vol. 27, no 3, 341-353 p.
Keyword [en]
Sarcopenia, Muscle mass, Aging, Cachexia
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-159063DOI: 10.1016/j.cger.2011.04.001ISI: 000294371700003OAI: oai:DiVA.org:uu-159063DiVA: diva2:442720
Available from: 2011-09-22 Created: 2011-09-21 Last updated: 2011-09-22Bibliographically approved

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