Ankle brachial index <0.9 underestimates the prevalence of peripheral artery occlusive disease assessed with whole-body magnetic resonance angiography in the elderly
2008 (English)In: Acta Radiologica, ISSN 0284-1851, E-ISSN 1600-0455, Vol. 49, no 2, 143-149 p.Article in journal (Refereed) Published
BACKGROUND: Whole-body magnetic resonance angiography (WBMRA) permits noninvasive vascular assessment, which can be utilized in epidemiological studies. PURPOSE: To assess the relation between a low ankle brachial index (ABI) and high-grade stenoses in the pelvic and leg arteries in the elderly. MATERIAL AND METHODS: WBMRA was performed in a population sample of 306 subjects aged 70 years. The arteries below the aortic bifurcation were graded after the most severe stenosis according to one of three grades: 0-49% stenosis, 50-99% stenosis, or occlusion. ABI was calculated for each side. RESULTS: There were assessable WBMRA and ABI examinations in 268 (right side), 265 (left side), and 258 cases (both sides). At least one > or =50% stenosis was found in 19% (right side), 23% (left side), and 28% (on at least one side) of the cases. The corresponding prevalences for ABI <0.9 were 4.5%, 4.2%, and 6.6%. An ABI cut-off value of 0.9 resulted in a sensitivity, specificity, and positive and negative predictive value of 20%, 99%, 83%, and 84% on the right side, and 15%, 99%, 82%, and 80% on the left side, respectively, for the presence of a > or =50% stenosis in the pelvic or leg arteries. CONCLUSION: An ABI <0.9 underestimates the prevalence of peripheral arterial occlusive disease in the general elderly population.
Place, publisher, year, edition, pages
2008. Vol. 49, no 2, 143-149 p.
Aged, Ankle/*blood supply, Arterial Occlusive Diseases/*diagnosis/epidemiology, Brachial Artery/*physiopathology, Cohort Studies, Contrast Media/administration & dosage, Female, Gadolinium DTPA/diagnostic use, Humans, Image Enhancement/methods, Imaging; Three-Dimensional/methods, Leg/blood supply, Magnetic Resonance Angiography/*methods, Male, Pelvis/blood supply, Peripheral Vascular Diseases/*diagnosis/epidemiology, Predictive Value of Tests, Prevalence, Prospective Studies, Sensitivity and Specificity, Severity of Illness Index, Whole Body Imaging/*methods
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-17337DOI: 10.1080/02841850701732957ISI: 000253642300005PubMedID: 18300136OAI: oai:DiVA.org:uu-17337DiVA: diva2:45108