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Focused ion beam in the study of biomaterials and biological matter
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences. (Materials in Medicine)
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.ORCID iD: 0000-0001-9529-650X
2012 (English)In: Advances in Materials Science and Engineering, ISSN 1687-8434, p. 841961-Article in journal (Refereed) Published
Abstract [en]

The application of focused ion beam (FIB) techniques in the life sciences has progressed by leaps and bounds over the past decade. A once dedicated ion beam instrument, the focused ion beam today is generally coupled with a plethora of complementary tools such as dual-beam scanning electron microscopy (SEM), environmental SEM, energy dispersive X-ray spectroscopy (EDX), or cryogenic possibilities. All of these additions have contributed to the advancement of focused ion beam use in the study of biomaterials and biological matter. Biomaterials, cells, and their interfaces can be routinely imaged, analyzed, or prepared for techniques such as transmission electron microscopy (TEM) with this comprehensive tool. Herein, we review the uses, advances, and challenges associated with the application of FIB techniques to the life sciences, with particular emphasis on TEM preparation of biomaterials, biological matter, and their interfaces using FIB.

Place, publisher, year, edition, pages
2012. p. 841961-
National Category
Medical Materials
Research subject
Engineering Science with specialization in Materials Science
Identifiers
URN: urn:nbn:se:uu:diva-160562DOI: 10.1155/2012/841961ISI: 000295670900001OAI: oai:DiVA.org:uu-160562DiVA, id: diva2:451395
Available from: 2011-10-25 Created: 2011-10-25 Last updated: 2018-02-08Bibliographically approved

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Grandfield, KathrynEngqvist, Håkan

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