Born to clot: the European burden.
1999 (English)In: British Journal of Haematology, ISSN 0007-1048, E-ISSN 1365-2141, Vol. 105, no 2, 564-6 p.Article in journal (Refereed) Published
Venous thrombosis is a common problem, predominantly afflicting people of European origin. This European predisposition has been explained to some extent by the recent characterization of factor V Leiden, and the G20210A prothrombin variant. Although it is clear that factor V Leiden is largely confined to Europeans, the world distribution of the prothrombin variant is not known. We have analysed samples from 22 different non-European countries and shown that this prothrombin variant is very rare outside Europe: one case occurring in India. The reason for the confined distribution of these two mutations is unclear.
Place, publisher, year, edition, pages
1999. Vol. 105, no 2, 564-6 p.
IdentifiersURN: urn:nbn:se:uu:diva-162858PubMedID: 10233439OAI: oai:DiVA.org:uu-162858DiVA: diva2:461748