Fasting capillary glucose as a screening test for gestational diabetes mellitus
2006 (English)In: BJOG: An International Journal of Obstetrics and Gynaecology, ISSN 1470-0328, Vol. 113, no 9, 1067-1071 p.Article in journal (Refereed) Published
Objective: To evaluate fasting capillary glucose as a screening test for gestational diabetes mellitus (GDM) compared with traditional risk factors and repeated random capillary glucose measurements. Design: Cross-sectional, population-based study. Setting: Maternal Health Care Clinics in Örebro County, Sweden. Population: An unselected population of women without diabetes. Methods: Fasting capillary glucose levels were measured at gestational weeks 28-32. Random capillary glucose levels were measured four to six times during pregnancy. Traditional risk factors for GDM were registered. GDM was diagnosed using a 75-g oral glucose tolerance test. Main outcome measures: Sensitivity, specificity, likelihood ratios. Results: In 55 of 3616 women participating in the study, GDM was diagnosed before 34 weeks of gestation. For fasting capillary glucose cutoff values between 4.0 and 5.0 mmol/l, sensitivity was in the range between 87 and 47% and specificity between 51 and 96%. Using a combined screening model of traditional risk factors with fasting capillary glucose at various cutoff values increased the sensitivity only slightly compared with using fasting capillary glucose alone. Conclusion: In this Swedish, unselected, low-risk population, fasting capillary glucose measurements were found to be an acceptable and useful screening test for GDM.
Place, publisher, year, edition, pages
2006. Vol. 113, no 9, 1067-1071 p.
Fasting capillary glucose, Gestational diabetes mellitus, Screening, Sensitivity, Specificity
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-18859DOI: 10.1111/j.1471-0528.2006.01032.xISI: 000240030600015PubMedID: 16956338OAI: oai:DiVA.org:uu-18859DiVA: diva2:46631