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Effects of iron supplementation on erythropoietic response in patients with cancer-associated anemia treated by means of erythropoietic stimulating agents
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. (Hematologi)
2011 (English)In: ISRN hematology, ISSN 2090-4428, Vol. 2011, 108397- p.Article in journal (Refereed) Published
Abstract [en]

During the past decade, intravenous iron supplementation to ESA (erythropoiesis-stimulating agent) therapy has emerged as an option to augment hemoglobin response in anemic cancer patients. In this paper, the results of seven published randomized clinical trials assessing the role of iron supplementation to ESA therapy in the hematology/oncology setting will be discussed. The pathogenetic mechanisms behind functional iron deficiency, a major reason for ESA hyporesponsiveness in cancer, will also be described.

Place, publisher, year, edition, pages
2011. Vol. 2011, 108397- p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-164768DOI: 10.5402/2011/108397PubMedID: 22111015Local ID: 108397OAI: oai:DiVA.org:uu-164768DiVA: diva2:469770
Available from: 2011-12-27 Created: 2011-12-27 Last updated: 2012-01-20Bibliographically approved

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