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Dietary intake and nutritional status in a Scandinavian adult cystic fibrosis-population compared with recommendations
Norwegian Resource Centre for Cystic Fibrosis, Oslo University Hospital, Norway.
Stockholm Cystic Fibrosis Center, Karolinska University Hospital, Karolinska Institutet Huddinge, Stockholm, Sweden.
Stockholm Cystic Fibrosis Center, Karolinska University Hospital, Karolinska Institutet Huddinge, Stockholm, Sweden.
Unit of Biostatistics and Epidemiology, Oslo University Hospital, Norway.
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2011 (English)In: Food & Nutrition Research, ISSN 1654-6628, Vol. 55, 7561- p.Article in journal (Refereed) Published
Abstract [en]


Malnutrition is a well-known complication in cystic fibrosis (CF). There is good evidence that maintaining a normal body-weight correlates well with improved survival in CF. Energy intake in excess of 120% of the estimated average requirement (EAR) has been advised since 1980s.


To investigate the nutritional intake and status in the adult Scandinavian CF-population.


A cross-sectional multi-centre study was used to investigate the nutritional status of 456 adult CF-patients (2003 2006). Height and weight were measured and body mass index (BMI) and z-scores were calculated. Pulmonary function was examined by dynamic spirometry. A 7-day pre-coded food record (FR) obtained energy and nutrient intake data in 180 patients.


The mean energy intake was 114 (SD 30.0)% of EAR and thus significantly lower than the target of 120% EAR (p< 0.001) for patients with pancreatic insufficiency (PI) (n=136). Mean BMI was 22.0 (SD 2.9), the prevalence of BMI <18 was 13% and the prevalence of BMI ≥25 was 15% (n=136). Mean BMI was 20.8 (SD 2.4) in PI-patients with FEV(1) <70% and 23.2% (SD 3.0), in PI-patients with FEV(1) ≥70%, mean difference 2.4, (95% CI: 1.5, 3.3) (p<0.001), but there was no difference in energy intake. BMI ≥18.5 and a reported energy intake <120% were revealed in 54% of the PI-patients.


The energy intake did not reach the recommended 120% EAR, but the prevalence of underweight was lower than reported in other studies. The recommendation may exceed the requirement for a number of CF-patients. The nutritional status must still be closely monitored and nutritional advice and intervention should be individualised and adjusted to actual needs.

Place, publisher, year, edition, pages
2011. Vol. 55, 7561- p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-164839DOI: 10.3402/fnr.v55i0.7561PubMedID: 22110412OAI: oai:DiVA.org:uu-164839DiVA: diva2:470413
Available from: 2011-12-29 Created: 2011-12-29 Last updated: 2012-03-12Bibliographically approved

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