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Metabolic Control, Treatment Satisfaction and Self-rated Health.: A comparative study in patients with type I diabetes that have undergone Islet cell transplantation or Pancreatic Transplantation.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences.
2011 (English)Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

ABSTRACT

Aim: To investigate metabolic control, treatment satisfaction and self-rated health in islet cell or pancreas transplantation IDDM patients (study group) compared to non-pancreatic transplanted IDDM patients (control group). 

Methods: 42 patients were included. 29 IDDM patients that had undergone islet cell or pancreatic transplantation (study group). 13 IDDM patients that had undergone living donor kidney transplantation or were on waitinglist for islet cell or pancreatic transplantation (control group). Measurements: fP-glucose, HbA1C, C-Peptide and Clarke Score, DTSQs and SRH. Data were collected for the study group three times and for control group one time. Statistical data were analyzed, for differences between study and control groups, correlations within the groups and differences over time in study group, with non-parametric analyzes.

Results: There were significant differences in metabolic control, treatment satisfaction and self-rated health between study and control groups. There were strong correlations within metabolic control and between treatment satisfaction and self-rated health. There were no significant differences in the variables over time for the study group.

Conclusion: Transplantation makes a large positive difference in treatment satisfaction and global health in IDDM patients. It is important to include patient-reported outcome measures as a complement to clinical and laboratory measures.

 

Keywords: Metabolic control, treatment satisfaction, self-rated health, islet cell transplantation, pancreatic transplantation and diabetes type 1.

Abstract [sv]

SAMMANFATTNING

 

Syfte: Att undersöka metabol kontroll, behandlingstillfredställelse och självskattad hälsa hos patienter med svårreglerad typ 1 diabetes som genomgått ö-cell- eller pankreastransplantation (studie grupp) samt hos patienter med svårreglerad typ 1 som inte genomgått transplantation (kontroll grupp).

Metod: 42 patienter med svårreglerad typ 1 diabetes inkluderades. 29 patienter som genomgått ö-cell- eller pankreastransplantation (studiegrupp). 13 patienter som antingen genomgått njurtransplantation med levande givare eller stått på väntelista för ö-cells- eller pankreastransplantation (kontrollgrupp). Mätvärden: fP-glucose, HbA1C, C-Peptid samt enkäten Clarke Score (metabol kontroll), enkäten DTSQs (behandlingstillfredställelse) och enkäten SRH (självskattad hälsa). Studiegruppen genomgick tre mätningar medan kontrollgruppen genomgick en mätning. Statistiska data analyserades, för skillnader mellan studie- och kontrollgrupp, korrelation inom grupperna och skillnader över tid för studiegruppen, med icke parametriska analyser i SPSS. 1C, C-Peptid samt frågeformuläret Clarke Score. januari 2010 - september en genomgått njuretranspl

Resultat: Det fanns signifikanta skillnader i metabol kontroll, behandlingstillfredställelse och självskattad hälsa mellan studiegrupp och kontrollgrupp. Det fanns starka samband inom metabol kontroll och mellan behandlingstillfredställelse och självskattad hälsa. Det fanns ingen signifikant skillnad i variablerna över tid för studiegruppen.

Konklusion: Transplantation utgör en stor positiv skillnad i behandlingstillfredställelse och självskattad hälsa för patienter med svårreglerad typ 1 diabetes. Patient rapporterade enkäter är ett viktigt komplement till kliniska och laboratorie mätvärden i vården av patienten.

 

Nyckelord: Metabol kontroll, Behandlingstillfredställelse, Självskattad hälsa, Ö-cellstransplantation, Pankreas transplantation och typ 1 diabetes.

Place, publisher, year, edition, pages
2011. , p. 49
Keyword [en]
Metabolic control, treatment satisfaction, self-rated health, islet cell transplantation, pancreatic transplantation and diabetes type 1
National Category
Nursing
Identifiers
URN: urn:nbn:se:uu:diva-164950OAI: oai:DiVA.org:uu-164950DiVA: diva2:471065
Subject / course
Caring Sciences
Educational program
Freestanding course
Presentation
2011-11-24, A4:106, BMC, Husargatan 3, Uppsala, 15:45 (Swedish)
Uppsok
Medicine
Supervisors
Examiners
Available from: 2012-01-24 Created: 2011-12-31 Last updated: 2012-01-24Bibliographically approved

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