In vivo Enhancement in Bioavailability of Atazanavir in the Presence of Proton-Pump Inhibitors using Mesoporous Materials
2012 (English)In: ChemMedChem, ISSN 1860-7179, Vol. 7, no 1, 43-8 p.Article in journal (Refereed) Published
Matters of the HAART! The current treatment for human immunodeficiency virus (HIV), HAART, makes use of a combination of antiretroviral drugs, which are poorly soluble in aqueous media. Enhancing the solubility of such drugs through the use of mesoporous materials could lead to improved treatment efficiency and might provide a solution to the drug-drug interaction problems associated with these types of therapeutic regimes.
Place, publisher, year, edition, pages
2012. Vol. 7, no 1, 43-8 p.
drug delivery, human immunodeficiency virus (HIV), mesoporous silica, proton-pump inhibitors, solubility
Research subject Engineering Science with specialization in Nanotechnology and Functional Materials; Engineering Science with specialization in Materials Science
IdentifiersURN: urn:nbn:se:uu:diva-165287DOI: 10.1002/cmdc.201100500ISI: 000298549100004PubMedID: 22144293OAI: oai:DiVA.org:uu-165287DiVA: diva2:472812
FunderSwedish Research Council