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Minimally invasive parathyroidectomy using the lateral focused mini-incision technique without intraoperative parathyroid hormone monitoring
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences.
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2007 (English)In: British Journal of Surgery, ISSN 0007-1323, E-ISSN 1365-2168, Vol. 94, no 3, 315-319 p.Article in journal (Refereed) Published
Abstract [en]

Background:Minimally invasive parathyroidectomy (MIP) involves scan-directed removal of a single adenoma through a 2·0-cm mini-incision without intraoperative monitoring. The aim of this study was to analyse the outcomes of MIP using such a simplified technique.Methods:The study group comprised 500 consecutive patients undergoing MIP via a lateral mini-incision from August 2000 to September 2005. Levels of parathyroid hormone (PTH) were measured after operation solely to aid informed discharge.Results:Some 97·4 per cent of patients were initially cured by MIP. Eight patients remained hypercalcaemic and a further five were normocalcaemic on the day after surgery but became hypercalcaemic again within 3 months of the procedure. Eleven of these patients were cured with subsequent re-exploration. Analysis of postoperative PTH data indicated that, at best, the use of intraoperative PTH measurement during surgery would have increased the cure rate by only a further 1 per cent. Three (0·6 per cent) of 500 patients had permanent recurrent laryngeal nerve palsy after MIP.Conclusion:MIP performed by the lateral focused mini-incision technique, without the use of intraoperative PTH monitoring, is a safe and effective procedure that results in outcomes equal to those of bilateral neck exploration.

Place, publisher, year, edition, pages
2007. Vol. 94, no 3, 315-319 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-22745DOI: 10.1002/bjs.5608PubMedID: 17205496OAI: oai:DiVA.org:uu-22745DiVA: diva2:50518
Available from: 2007-01-22 Created: 2007-01-22 Last updated: 2010-03-25Bibliographically approved

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Publisher's full textPubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=17205496&dopt=Citation

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