Drug prescriptions of adults with adolescent depression in a community sample
2012 (English)In: Pharmacoepidemiology and Drug Safety, ISSN 1053-8569, E-ISSN 1099-1557, Vol. 21, no 2, 130-136 p.Article in journal (Refereed) Published
The prescription drugs have, to our knowledge, not been much studied in epidemiological samples with long-term follow-up. Accordingly, our purpose was to analyze the use of prescription drugs in adults with adolescent depression.
A population-based cohort of adolescents (n = 2465) was screened for the presence of depressive symptoms and diagnosed according to a structured interview. Totally, 362 individuals were identified as depressed and compared with 250 non-depressed controls. The prescription drugs were evaluated at the age of 29-31 years from a register kept by the National Health and Welfare Board.
The formerly depressed females received significantly more prescription drugs, such as antidepressants, antiepileptics, antibacterials, antimycotics, and antihistamines for systemic use as well as other drugs, compared with controls (15.6 +/- 27.4 vs 8.2 +/- 7.4 recipes, p < 0.001). Formerly depressed males did not differ from controls regarding prescription drugs.
The females but not males with adolescent depression subsequently received more prescription drugs than non-depressed peers. Depressed female adolescents received more psychotropic and non-psychotropic drugs later in life compared to the non-depressed. This might be as a result of physical illnesses, different treatment-seeking behaviors, or somatizing reactions.
Place, publisher, year, edition, pages
2012. Vol. 21, no 2, 130-136 p.
adolescent depression, follow-up, prescription drugs
Medical and Health Sciences
Research subject Child and Youth Psychiatry
IdentifiersURN: urn:nbn:se:uu:diva-169101DOI: 10.1002/pds.2120ISI: 000299549600002OAI: oai:DiVA.org:uu-169101DiVA: diva2:506058