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Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Cell Biology.
Department of Genetics and Pathology.
2006 (English)In: Diabetologia, ISSN 0012-186X, Vol. 49, no 6, 1237-46 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2006. Vol. 49, no 6, 1237-46 p.
Keyword [en]
Amyloid/genetics/*metabolism, Amyloidosis/genetics, Animals, Apoptosis, Guinea Pigs, Humans, Insulin-Secreting Cells/cytology/*physiology/ultrastructure, Islets of Langerhans Transplantation/*physiology, Mice, Mice; Nude, Mice; Transgenic, Microscopy; Immunoelectron, Protein Precursors/*genetics, Protein Processing; Post-Translational, Rabbits, Transplantation; Heterologous
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URN: urn:nbn:se:uu:diva-22889PubMedID: 16570161OAI: oai:DiVA.org:uu-22889DiVA: diva2:50662
Available from: 2007-01-23 Created: 2007-01-23 Last updated: 2011-01-11

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Andersson, AWestermark, P

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