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The number of unrecognized myocardial infarction scars detected at DE-MRI increase during a 5-year follow-up
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Radiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Radiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Radiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Cardiovascular epidemiology.
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2017 (English)In: European Radiology, ISSN 0938-7994, E-ISSN 1432-1084, Vol. 27, no 2, 715-722 p.Article in journal (Refereed) Published
Abstract [en]

Objectives

In an elderly population, the prevalence of unrecognized myocardial infarction (UMI) scars found via late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) imaging was more frequent than expected. This study investigated whether UMI scars detected with LGE-CMR at age 70 would be detectable at age 75 and whether the scar size changed over time.

Methods

From 248 participants that underwent LGE-CMR at age 70, 185 subjects underwent a follow-up scan at age 75. A myocardial infarction (MI) scar was defined as late enhancement involving the subendocardium.

Results

In the 185 subjects that underwent follow-up, 42 subjects had a UMI scar at age 70 and 61 subjects had a UMI scar at age 75. Thirty-seven (88 %) of the 42 UMI scars seen at age 70 were seen in the same myocardial segment at age 75. The size of UMI scars did not differ between age 70 and 75.

Conclusions

The prevalence of UMI scars detected at LGE-CMR increases with age. During a 5-year follow-up, 88 % (37/42) of the UMI scars were visible in the same myocardial segment, reassuring that UMI scars are a consistent finding. The size of UMI scars detected during LGE-CMR did not change over time.

Place, publisher, year, edition, pages
2017. Vol. 27, no 2, 715-722 p.
Keyword [en]
Unrecognized myocardial infarction, delayed-enhancement magnetic resonance imaging, follow-up study, epidemiology
National Category
Radiology, Nuclear Medicine and Medical Imaging Cardiac and Cardiovascular Systems
Research subject
Radiology; Cardiology; Epidemiology
Identifiers
URN: urn:nbn:se:uu:diva-172069DOI: 10.1007/s00330-016-4439-7ISI: 000392142000032PubMedID: 27255402OAI: oai:DiVA.org:uu-172069DiVA: diva2:513403
Funder
Swedish Research Council, k2013-64x-08268-3
Available from: 2012-04-02 Created: 2012-04-02 Last updated: 2017-12-07Bibliographically approved

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Themudo, RaquelJohansson, Lars E.Ebeling Barbier, CharlotteLind, LarsAhlström, HåkanBjerner, Tomas

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Radiology, Nuclear Medicine and Medical ImagingCardiac and Cardiovascular Systems

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