uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Relationship between illness severity scores in acute kidney injury
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
Show others and affiliations
2012 (English)In: Critical care and resuscitation, ISSN 1441-2772, Vol. 14, no 1, 53-55 p.Article in journal (Refereed) Published
Abstract [en]

Background: In the field of critical care nephrology, recent publications have used different illness severity scoring systems, making outcome comparisons difficult.

Objective: To establish a methodology to translate one illness severity scoring system into another for critically ill patients with acute kidney injury (AKI). Design: Statistical analysis of prospectively obtained data.

Methods: Using data from the Australian and New Zealand Intensive Care Society Adult Patient Database, we obtained Acute Physiology and Chronic Health Evaluation (APACHE) II, APACHE III and Simplified Acute Physiology Score (SAPS II) scores for all patients admitted with AKI. We applied correlation and linear regression analyses as well as cross-validation with holdout samples.

Results: Between 2001 and 2010, the three illness severity scores were obtained in 636 431 admissions. Of these, 37 203 fulfilled the APACHE score criteria for AKI. The coefficient of determination (R-2) between APACHE II and APACHE III scores was 0.66. The overall model was APACHE III = 3.13 x APACHE II + 7.99 (P<0.001). Similarly, the R-2 between APACHE III and the SAPS II scores was 0.78. The overall model was APACHE III = 1.49 x SAPS II + 15.5 (P<0.001). The R-2 between APACHE II and SAPS II scores was 0.62. The overall model was APACHE II = 0.35 x SAPS II + 9.3 (P<0.001).

Conclusions: Simple, robust translational formulae can be developed to allow clinicians to compare illness severity of patients with AKI when illness severity is expressed with different scoring systems.

Place, publisher, year, edition, pages
2012. Vol. 14, no 1, 53-55 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-172042ISI: 000301210300010OAI: oai:DiVA.org:uu-172042DiVA: diva2:513462
Available from: 2012-04-02 Created: 2012-04-01 Last updated: 2012-04-02Bibliographically approved

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Lipcsey, Miklos
By organisation
Anaesthesiology and Intensive Care
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

Total: 299 hits
ReferencesLink to record
Permanent link

Direct link