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Molecular shape land size of hyaluronic acid and chondroitinsulphuric acid
Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy, Mathematics and Science Section.
Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy, Mathematics and Science Section.
1944 (English)In: Nature, ISSN 0028-0836, E-ISSN 1476-4687, Vol. 153, 587-587 p.Article in journal, Letter (Refereed) Published
Abstract [en]

THE hyaluronic acid, which was first isolated from vitreous humor1, and later has been found in, for example, synovial fluid2 and navel cord tissue3 gives highly viscous solutions and is often precipitated as fibres. Its molecules have therefore been assumed to have a chain structure. The Chondroitinsulphuric acid gives less viscous solutions and is precipitated at most in small fibres of little coherence. Levene and La Forge4 tentatively expressed its structural formula as a tetrasaccharide, a view which seemed to receive support from von Fürth and Bruno5, who by the aid of Northrop’s diffusion method obtained a molecular weight of about 975.

Place, publisher, year, edition, pages
1944. Vol. 153, 587-587 p.
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Natural Sciences
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URN: urn:nbn:se:uu:diva-172125DOI: 10.1038/153587a0ISI: 000202568100344OAI: oai:DiVA.org:uu-172125DiVA: diva2:513594
Available from: 2012-04-03 Created: 2012-04-02 Last updated: 2017-12-07Bibliographically approved

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