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A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences. (Pharmacogenetics)
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2006 (English)In: Clin Pharmacol Ther, ISSN 0009-9236, Vol. 79, no 1, 103-13 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2006. Vol. 79, no 1, 103-13 p.
Keyword [en]
Animals, Anticonvulsants/pharmacokinetics, Antidepressive Agents/*pharmacokinetics/therapeutic use, Aryl Hydrocarbon Hydroxylases/*genetics, China/epidemiology, Electrophoretic Mobility Shift Assay, Enzyme Inhibitors/*pharmacokinetics/therapeutic use, Ethiopia/epidemiology, Gene Frequency, Genes; Reporter/genetics, Genotype, Humans, Male, Mephenytoin/pharmacokinetics, Mice, Mixed Function Oxygenases/*genetics, Mutation, Omeprazole/pharmacokinetics/therapeutic use, Phenotype, Plasmids/genetics, Proton Pumps/*antagonists & inhibitors, Reverse Transcriptase Polymerase Chain Reaction, Sweden/epidemiology, Transfection, Variation (Genetics)
URN: urn:nbn:se:uu:diva-23734PubMedID: 16413245OAI: oai:DiVA.org:uu-23734DiVA: diva2:51508
Available from: 2008-06-18 Created: 2008-06-18 Last updated: 2011-01-11

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Dahl, Marja-Liisa
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