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Immunogenicity of delayed TBE-vaccine booster
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm , Centrum för klinisk forskning i D län (CKFD).
2012 (English)In: Vaccine, ISSN 0264-410X, E-ISSN 1873-2518, Vol. 30, no 3, 499-502 p.Article in journal (Refereed) Published
Abstract [en]

Information is scarce regarding the antibody response when TBE-vaccine booster doses are delayed, which is a common situation in daily life. We have investigated the immune response after a delayed booster dose compared to a normal booster interval in an every-day setting. Overall, 250/260 (96%) of the study participants had neutralizing antibodies post-booster, with no significant difference between normal and delayed booster intervals. Based on our findings we propose that healthy individuals who have failed adherence to the recommended schedule of TBE-vaccination can be given a delayed dose without concern of immunogenicity.

Place, publisher, year, edition, pages
2012. Vol. 30, no 3, 499-502 p.
Keyword [en]
TBE, Vaccination, Booster dose, Neutralizing antibodies
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-173048DOI: 10.1016/j.vaccine.2011.11.061ISI: 000301812300001OAI: oai:DiVA.org:uu-173048DiVA: diva2:516468
Available from: 2012-04-18 Created: 2012-04-18 Last updated: 2012-04-18Bibliographically approved

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