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Clinical application of a semimechanistic-physiologic population PK/PD model for neutropenia following pemetrexed therapy.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
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2006 (English)In: Cancer Chemother Pharmacol, ISSN 0344-5704, Vol. 57, no 4, 427-35 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2006. Vol. 57, no 4, 427-35 p.
Keyword [en]
Adult, Aged, Antimetabolites; Antineoplastic/administration & dosage/*adverse effects/*pharmacokinetics, Area Under Curve, Avitaminosis/blood, Biological Markers, Clinical Trials; Phase II, Dose-Response Relationship; Drug, Female, Glutamates/administration & dosage/*adverse effects/*pharmacokinetics, Guanine/administration & dosage/adverse effects/*analogs & derivatives/pharmacokinetics, Humans, Leukocyte Count, Male, Middle Aged, Models; Statistical, Neutropenia/*chemically induced/epidemiology/prevention & control, Neutrophils, Population
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URN: urn:nbn:se:uu:diva-23895PubMedID: 16322992OAI: oai:DiVA.org:uu-23895DiVA: diva2:51669
Available from: 2007-02-01 Created: 2007-02-01 Last updated: 2011-01-11

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Karlsson, Mats O

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