Femtosecond diffractive imaging with a soft-X-ray free-electron laser
2006 (English)In: Nature Physics, ISSN 1745-2473, E-ISSN 1745-2481, Vol. 2, no 12, 839-843 p.Article in journal (Refereed) Published
Theory predicts(1-4) that, with an ultrashort and extremely bright coherent X-ray pulse, a single diffraction pattern may be recorded from a large macromolecule, a virus or a cell before the sample explodes and turns into a plasma. Here we report the first experimental demonstration of this principle using the FLASH soft-X-ray free-electron laser. An intense 25 fs, 4 x 10(13) W cm(-2) pulse, containing 10(12) photons at 32 nm wavelength, produced a coherent diffraction pattern from a nanostructured non-periodic object, before destroying it at 60,000 K. A novel X-ray camera assured single-photon detection sensitivity by filtering out parasitic scattering and plasma radiation. The reconstructed image, obtained directly from the coherent pattern by phase retrieval through oversampling(5-9), shows no measurable damage, and is reconstructed at the diffraction-limited resolution. A three-dimensional data set may be assembled from such images when copies of a reproducible sample are exposed to the beam one by one(10).
Place, publisher, year, edition, pages
2006. Vol. 2, no 12, 839-843 p.
IdentifiersURN: urn:nbn:se:uu:diva-24416DOI: 10.1038/nphys461ISI: 000242478000021OAI: oai:DiVA.org:uu-24416DiVA: diva2:52190