Imaging the islet graft by positron emission tomography
2012 (English)In: European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, E-ISSN 1619-7089, Vol. 39, no 3, 533-542 p.Article, review/survey (Refereed) Published
Clinical islet transplantation is being investigated as a permanent cure for type 1 diabetes mellitus (T1DM). Currently, intraportal infusion of islets is the favoured procedure, but several novel implantation sites have been suggested. Noninvasive longitudinal methodologies are an increasingly important tool for assessing the fate of transplanted islets, their mass, function and early signs of rejection. This article reviews the approaches available for islet graft imaging by positron emission tomography and progress in the field, as well as future challenges and opportunities.
Place, publisher, year, edition, pages
2012. Vol. 39, no 3, 533-542 p.
Islet transplantation, Islet imaging, Rejection, Beta cell mass, Positron emission tomography
Radiology, Nuclear Medicine and Medical Imaging
IdentifiersURN: urn:nbn:se:uu:diva-173957DOI: 10.1007/s00259-011-1928-4ISI: 000302287200021OAI: oai:DiVA.org:uu-173957DiVA: diva2:525901