uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Enantioselective addition of aldehydes to amines via combined catalytic biomimetic oxidation and organocatalytic C-C bond formation.
2005 (English)In: Tetrahedron Letters, ISSN 0040-4039, E-ISSN 1873-3581, Vol. 46, no 23, 3965-3968 p.Article in journal (Refereed) Published
Abstract [en]

The biomimetic catalytic enantioselective addn. of aldehydes to amines is reported. This was accomplished by combining biomimetic coupled catalytic aerobic oxidn. of amines involving ruthenium-induced dehydrogenation and organocatalytic asym. Mannich reactions. The one-pot reactions furnished β-amino aldehyde and α-amino acid derivs. in high yields with excellent chemoselectivity and enantioselectivity. [on SciFinder(R)]

Place, publisher, year, edition, pages
2005. Vol. 46, no 23, 3965-3968 p.
Keyword [en]
amine ruthenium hydroquinone cobalt biomimetic oxidn propanal addn proline, amino aldehyde asym prepn redn, alc amino asym prepn, ruthenium hydroquinone cobalt biomimetic oxidn catalyst, proline asym Mannich reaction catalyst
National Category
Natural Sciences
URN: urn:nbn:se:uu:diva-174521DOI: 10.1016/j.tetlet.2005.04.047OAI: oai:DiVA.org:uu-174521DiVA: diva2:527597
CAPLUS AN 2005:411368(Journal)Available from: 2012-05-21 Created: 2012-05-21 Last updated: 2012-05-21

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Samec, Joseph S. M.
In the same journal
Tetrahedron Letters
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 274 hits
ReferencesLink to record
Permanent link

Direct link