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Low frequency of phlebographic deep vein thrombosis after laparoscopic cholecystectomy: a pilot study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Upper Abdominal Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology, Radiology. (Nyman)
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2006 (English)In: Clinical and applied thrombosis/hemostasis, ISSN 1076-0296, E-ISSN 1938-2723, Vol. 12, no 4, 421-426 p.Article in journal (Refereed) Published
Abstract [en]

To investigate the rate of deep vein thrombosis (DVT) after laparoscopic surgery, 50 patients underwent bilateral phlebography 7-11 days after laparoscopic cholecystectomy (LC). All received thromboembolism prophylaxis, either low molecular weight heparin (LMWH) or dextran. Three patients were converted to open cholecystectomy. D-dimer was investigated preoperatively, on day 1 and on the day of phlebography. One asymptomatic DVT was found. One phlebogram was incomplete. Seven phlebograms were not optimal but of sufficient quality to rule out DVT. The frequency of DVT was thus 1 of 49 or 2.0% (95% confidence interval, 0-6.0%). No anticoagulants were prescribed after discharge. No patient developed late thromboembolic complications. D-dimer values increased significantly at day 1 and were further increased at the time of phlebography. The frequency of phlebographical DVTs thus seems to be low despite prophylaxis of questionable efficacy. The D-dimer values, however, suggest that the effects of LC on coagulation/fibrinolysis have a duration of longer than 1 week.

Place, publisher, year, edition, pages
2006. Vol. 12, no 4, 421-426 p.
Keyword [en]
thromboembolic complications, deep vein thrombosis, laparoscopic cholecystectomy, phlebography
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-25050DOI: 10.1177/1076029606293425ISI: 000240762400003PubMedID: 17000886OAI: oai:DiVA.org:uu-25050DiVA: diva2:52824
Available from: 2007-05-08 Created: 2007-05-08 Last updated: 2017-12-07Bibliographically approved

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Björck, MartinRasmussen, IbNyman, RickardBergqvist, David

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