Diabetes-induced decrease in renal oxygen tension: effects of an altered metabolism
2006 (English)In: Advances in Experimental Medicine and Biology, ISSN 0065-2598, Vol. 578, 161-166 p.Article in journal (Refereed) Published
During conditions with experimental diabetes mellitus, it is evident that several alterations in renal oxygen metabolism occur, including increased mitochondrial respiration and increased lactate accumulation in the renal tissue. Consequently, these alterations will contribute to decrease the interstitial pO2, preferentially in the renal medulla of animals with sustained long-term hyperglycemia.
Place, publisher, year, edition, pages
2006. Vol. 578, 161-166 p.
Animals, Diabetes Mellitus; Experimental/metabolism/physiopathology, Diabetic Nephropathies/*metabolism/*physiopathology, Humans, Kidney/*metabolism/physiology, Oxygen Consumption/physiology
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-25052PubMedID: 16927687OAI: oai:DiVA.org:uu-25052DiVA: diva2:52826