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Bifurcation phenomena in an impulsive model of non-basal testosterone regulation
Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology, Division of Systems and Control. Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology, Computer Systems. Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology, Automatic control.
2012 (English)In: Chaos, ISSN 1054-1500, E-ISSN 1089-7682, Vol. 22, no 1, 013121- p.Article in journal (Refereed) Published
Abstract [en]

Complex nonlinear dynamics in a recent mathematical model of non-basal testosterone regulation are investigated. In agreement with biological evidence, the pulsatile (non-basal) secretion of testosterone is modeled by frequency and amplitude modulated feedback. It is shown that, in addition to already known periodic motions with one and two pulses in the least period of a closed-loop system solution, cycles of higher periodicity and chaos are present in the model in hand. The broad range of exhibited dynamic behaviors makes the model highly promising in model-based signal processing of hormone data. 

Place, publisher, year, edition, pages
2012. Vol. 22, no 1, 013121- p.
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Computer and Information Science Biological Sciences
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URN: urn:nbn:se:uu:diva-174587DOI: 10.1063/1.3685519ISI: 000302576900021OAI: oai:DiVA.org:uu-174587DiVA: diva2:529205
Available from: 2012-05-29 Created: 2012-05-22 Last updated: 2017-12-07Bibliographically approved

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Medvedev, Alexander

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