An image analysis toolbox for high-throughput C. elegans assays
2012 (English)In: Nature Methods, ISSN 1548-7091, E-ISSN 1548-7105, Vol. 9, no 7, 714-716 p.Article in journal (Refereed) Published
We present a toolbox for high-throughput screening of image-based Caenorhabditis elegans phenotypes. The image analysis algorithms measure morphological phenotypes in individual worms and are effective for a variety of assays and imaging systems from different laboratories. The toolbox is available via the open-source CellProfiler project and enables objective scoring of whole-animal high-throughput image-based assays using this unique model organism for the study of diverse biological pathways relevant to human disease.
Place, publisher, year, edition, pages
2012. Vol. 9, no 7, 714-716 p.
C. elegans, image analysis, image based screening
Medical Image Processing
Research subject Computerized Image Processing
IdentifiersURN: urn:nbn:se:uu:diva-175224DOI: 10.1038/nmeth.1984ISI: 000305942200026PubMedID: 22522656OAI: oai:DiVA.org:uu-175224DiVA: diva2:530598