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Potential for clinical radionuclide-based imaging and therapy of common cancers expressing EGFR-family receptors
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Biomedical Radiation Sciences.
2012 (English)In: Tumor Biology, ISSN 1010-4283, E-ISSN 1423-0380, Vol. 33, no 3, 653-659 p.Article in journal (Refereed) Published
Abstract [en]

High expression of epidermal growth factor receptor (EGFR)-family receptors, especially EGFR, HER2, and HER3, makes them interesting for targeted radionuclide-based imaging and therapy of disseminated cancer. The expression in some commonly occurring cancers such as breast, prostate, colorectal, and urinary bladder cancers is summarized. Possible strategies for radionuclide-based imaging and therapy are briefly discussed, especially in relation to the receptor expression in metastases.

Place, publisher, year, edition, pages
2012. Vol. 33, no 3, 653-659 p.
Keyword [en]
EGFR, HER2, HER3, HER4, Imaging, Metastasis, Radionuclide, Receptors, Therapy
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-175187DOI: 10.1007/s13277-011-0307-xISI: 000303530200009OAI: oai:DiVA.org:uu-175187DiVA: diva2:531882
Available from: 2012-06-08 Created: 2012-06-04 Last updated: 2012-06-08Bibliographically approved

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Carlsson, Jörgen
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