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Pulmonary blood flow generates cardiogenic oscillations
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2009 (English)In: Respiratory Physiology & Neurobiology, ISSN 1569-9048, E-ISSN 1878-1519, Vol. 167, no 3, 247-254 p.Article in journal (Refereed) Published
Abstract [en]

Cardiogenic oscillations are small waves produced by heartbeats, which are superimposed on the pressure and flow signals at the airway opening. The aim of this study was to investigate the role of the two main factors believed to generate these oscillations: (1) contact between heart and lungs and (2) pulmonary blood flow. We studied 15 heart surgery patients on cardiopulmonary bypass so both factors could be manipulated independently.

At minimal heart–lung contact pressure and flow oscillations were larger than during maximal contact (1.20 ± 0.17 cmH2O and 2.36 ± 0.08 L min−1 vs 0.92 ± 0.15 cmH2O and 1.78 ± 0.26 L min−1, mean ± SD, p < 0.05). Cardiogenic oscillations for pressure and flow were smaller at 50% compared to 100% pulmonary blood flow (0.80 ± 0.12 cmH2O and 1.56 ± 0.34 L min−1 vs 1.19 ± 0.14 cmH2O and 2.38 ± 0.19 L min−1). We conclude that the amount of pulmonary blood flow and not the contact between heart and lungs is the main factor determining the amplitude of cardiogenic oscillations.

Place, publisher, year, edition, pages
2009. Vol. 167, no 3, 247-254 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-176051DOI: 10.1016/j.resp.2009.04.026PubMedID: 19439200OAI: oai:DiVA.org:uu-176051DiVA: diva2:534074
Available from: 2012-06-15 Created: 2012-06-15 Last updated: 2012-06-18Bibliographically approved

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