uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Near-infrared spectroscopy of the thenar eminence: comparison of dynamic testing protocols
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
2012 (English)In: Critical Care and Resuscitation, ISSN 1441-2772, Vol. 14, no 2, 142-147 p.Article in journal (Refereed) Published
Abstract [en]

Background: Near-infrared spectroscopy of the thenar eminence (NIRSth) is a non-invasive bedside method for assessing tissue oxygenation. The vascular occlusion test (VOT) with a pressure cuff can be used to provide a dynamic assessment of the tissue oxygenation response to ischaemia. VOT has been applied to assess the microcirculation by NIRSth in critically ill patients. The optimal mode of performing such VOT, however, remains controversial. Design, participants and setting: Prospective observational study among a cohort of 11 healthy volunteers in a tertiary intensive care department. Intervention: Measurement of NIRS-derived parameters using 1-, 2- and 3-minute VOTs or VOT to 40% tissue oxygen saturation (StO(2)). Main outcome measure: Changes in StO(2) and tissue haemoglobin index (THI) over time, and relative change from baseline for StO(2) and THI. Results: Mean baseline StO(2) was 80% (SD, 5%) and mean THI was 13.7 (SD, 1.9). The lowest StO(2) at the end of the VOT was 39% (SD, 13%) and 39% (SD, 2%) in the 3-minute and the 40% StO(2) VOTs, respectively. The duration of the 40% StO(2) VOT ranged from 1:35 to 8:21 minutes (median, 3:29 min). There was a difference between the StO(2) curves for the 3-minute and 40% StO(2) VOT (P = 0.005) but not the THI curves. Reported pain score was a median of 3.5 (IQR, 2.5-5.5) and 4 (IQR 2-4) for the 3-minute and 40% StO(2) VOTs, respectively. Conclusions: The 3-minute VOT and the 40% StO(2) appear equivalent. However, the 3-minute VOT carries a degree of decreased patient discomfort and shorter overall duration of execution.

Place, publisher, year, edition, pages
2012. Vol. 14, no 2, 142-147 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-177231ISI: 000304794400008OAI: oai:DiVA.org:uu-177231DiVA: diva2:540301
Available from: 2012-07-09 Created: 2012-07-04 Last updated: 2012-07-09Bibliographically approved

Open Access in DiVA

No full text

Other links


Search in DiVA

By author/editor
Lipcsey, Miklos
By organisation
Anaesthesiology and Intensive Care
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 249 hits
ReferencesLink to record
Permanent link

Direct link