Physical activity, obesity, and risk of colon and rectal cancer in a cohort of Swedish men
2006 (English)In: European Journal of Cancer, ISSN 0959-8049, E-ISSN 1879-0852, Vol. 42, no 15, 2590-2597 p.Article in journal (Refereed) Published
We investigated the association between physical activity and colorectal cancer risk in a cohort of Swedish men. Information on physical activity was obtained at baseline in 1997 with a self-administered questionnaire from 45,906 men who were cancer-free at enrollment. During a mean follow-up of 7.1 years, 496 cases of colorectal cancer occurred.. Leisure-time physical activity was inversely associated with colorectal cancer risk; the multivariate hazard ratio (HR) for 60 min or more per day of leisure-time physical activity compared with less than 10 min per day was 0.57 (95% CI 0.41-0.79; P for trend = 0.001). Results were similar for colon (HR = 0.56; 95% CI 0.37-0.83) and rectal cancer (HR = 0.59; 95% CI 0.34-1.02). Home/housework activity was inversely associated with colon cancer risk (HR = 0.68; 95% CI 0.48-0.96). No association was observed for work/occupational activity. These results support a role of physical activity in reducing the risk of colon and rectal cancer.
Place, publisher, year, edition, pages
2006. Vol. 42, no 15, 2590-2597 p.
anthropometry, body mass index, cohort studies, colorectal neoplasms, exercise, physical activity, prospective studies
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-26547DOI: 10.1016/j.ejca.2006.04.015ISI: 000241926300033PubMedID: 16914307OAI: oai:DiVA.org:uu-26547DiVA: diva2:54321