uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Metabolism of the Vitamin-A-Transporting Protein Complex: Turnover of Retinol-Binding Protein, Prealbumin and Vitamin A in a Primate (Macaca Irus)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine.
1972 (English)In: Scandinavian Journal of Clinical and Laboratory Investigation, ISSN 0036-5513, Vol. 30, no 4, 349-360 p.Article in journal (Refereed) Published
Abstract [en]

The kinetics of the specific retinol transport system in plasma, including the retinol-binding protein (RBP) and prealbumin, have been investigated in the Cynomolgus monkey (Macaca irus) with iodine-labelled and endogenously 35S-labelled proteins as tracers. The biological half-times were 1.9 hours for RBP in free form. 6.6 hours for RBP interacting with prealbumin, and 22.5 hours for prealbumin itself. The results indicate that RBP is degraded mainly when in free form. The turnover of labelled retinol attached to RBP was compatible with a certain reutilization of the vitamin as contrasted to RBP.

Place, publisher, year, edition, pages
1972. Vol. 30, no 4, 349-360 p.
Keyword [en]
Cynomolgus, Macaca irus, monkey, prealbumin, protein metabolism, retinol-binding protein, vitamin A
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-180693DOI: 10.3109/00365517209080270ISI: A1972O194300002OAI: oai:DiVA.org:uu-180693DiVA: diva2:551292
Available from: 2012-09-10 Created: 2012-09-10 Last updated: 2012-09-10Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text
By organisation
Faculty of Medicine
In the same journal
Scandinavian Journal of Clinical and Laboratory Investigation
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 165 hits
ReferencesLink to record
Permanent link

Direct link