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Sex-dependent effects of prenatal 2,4,5-trichlorophenoxy-acetic acid on rats open-field behavior
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine.
1972 (English)In: Physiology and Behavior, ISSN 0031-9384, E-ISSN 1873-507X, Vol. 9, no 3, 357-360 p.Article in journal (Refereed) Published
Abstract [en]

Female rats were orally injected with a single dose of 2,4,5-trichlorophen-oxyacetic acid (2,4,5-T) during early pregnancy. Their offspring were subjected to open-field testing for two consecutive days at 90 days of age. It was found that male offspring of treated mothers were significantly more explorative than male offspring of control mothers. No effect of treatment on emotional reactivity was observed in male groups. Open-field behavior of female offspring was not affected by the treatment. The results are discussed with regard to mechanisms, mediating the observed effects.

Place, publisher, year, edition, pages
1972. Vol. 9, no 3, 357-360 p.
National Category
Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-180689DOI: 10.1016/0031-9384(72)90159-XISI: A1972O832000013OAI: oai:DiVA.org:uu-180689DiVA: diva2:551383
Available from: 2012-09-11 Created: 2012-09-10 Last updated: 2017-12-07Bibliographically approved

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