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Competitive Inhibition of Sephadex-Bound Chymotrypsin and Trypsin
Uppsala University, Disciplinary Domain of Science and Technology, Faculty of Mathematics and Science.
Uppsala University, Disciplinary Domain of Science and Technology, Faculty of Mathematics and Science.
1972 (English)In: Hoppe-Seyler´s Zeitschrift für physiologische Chemie, ISSN 0018-4888, Vol. 353, no 12, 1850-1854 p.Article in journal (Refereed) Published
Abstract [en]

Summary: The effect of competitive inhibitors onparticulate chymotrypsin and trypsin is described.Whereas the hydrolysis of slow substrates is inhibitedin the same way as for the soluble enzymes, the hydrolysis of fast substrates is inhibited to amarkedly less extent. After solubilization of the enzyme-carrier conjugate by dextranase, the propertiesof the free enzymes are regained. Implications for the study of naturally membrane-boundenzymes are discussed

Place, publisher, year, edition, pages
1972. Vol. 353, no 12, 1850-1854 p.
National Category
Chemical Sciences
Identifiers
URN: urn:nbn:se:uu:diva-180769DOI: 10.1515/bchm2.1972.353.2.1850ISI: A1972O388100008OAI: oai:DiVA.org:uu-180769DiVA: diva2:551736
Available from: 2012-09-12 Created: 2012-09-10 Last updated: 2012-09-12Bibliographically approved

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