The adhesion and spreading of thrombocyte vesicles on electrode surfaces
2008 (English)In: Bioelectrochemistry, ISSN 1567-5394, E-ISSN 1878-562X, Vol. 74, 210-216 p.Article in journal (Refereed) Published
The interaction of thrombocyte vesicles with the surface of metal electrodes, i.e., mercury, gold and gold electrodes modified with self assembled monolayers (SAM), was studied with the help of chronoamperometry, atomic force microscopy, and quartz crystal microbalance measurements. The experimental results show that the interaction of the thrombocyte vesicles with the surface of the electrodes depends on the hydrophobicity of the latter: whereas on very hydrophobic surfaces (mercury and gold functionalized with SAM) the thrombocyte vesicles disintegrate and form a monolayer of lipids. on the less hydrophobic gold surface a bilayer is formed. The chronoamperometric measurements indicate the possibility of future applications to probe membrane properties of thrombocytes. (C) 2008 Elsevier B.V. All rights reserved.
Place, publisher, year, edition, pages
2008. Vol. 74, 210-216 p.
Thrombocyte vesicles; Chronoamperometry; Quartz crystal microbalance; Adhesion; Mercury electrode
IdentifiersURN: urn:nbn:se:uu:diva-180979DOI: 10.1016/j.bioelechem.2008.08.003OAI: oai:DiVA.org:uu-180979DiVA: diva2:552512