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Effects of dextranation on the pharmacokinetics of short peptides. A PET study on mEGF
Uppsala University.
Uppsala University.
Uppsala University.
Uppsala University.
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1999 (English)In: BIOCONJUGATE CHEMISTRY, ISSN 1043-1802, Vol. 10, no 6, 938-946 p.Article in journal (Other academic) Published
Abstract [en]

The effects of dextranation on the biodistribution of mouse epidermal growth factor (mEGF, 6 kDa) were assessed. By reductive amination, mEGF was coupled to 13 and 46 kDa dextran. The two dextranated conjugates and free mEGF were labeled with the positron

Place, publisher, year, edition, pages
AMER CHEMICAL SOC , 1999. Vol. 10, no 6, 938-946 p.
Keyword [en]
EPIDERMAL-GROWTH-FACTOR; NEUTRON-CAPTURE THERAPY; TUMOR-BEARING MICE; RENAL UPTAKE; FACTOR-RECEPTOR; ANTIBODY FRAGMENTS; KINETIC-ANALYSIS; BLADDER-CANCER; RAT-LIVER; CELL-LINE
Identifiers
URN: urn:nbn:se:uu:diva-27374OAI: oai:DiVA.org:uu-27374DiVA: diva2:55269
Note
Addresses: Tolmachev V, Univ Uppsala, Box 535, S-75121 Uppsala, Sweden. Univ Uppsala, S-75121 Uppsala, Sweden. Univ Uppsala, Dept Diagnost Radiol, S-75185 Uppsala, Sweden. Univ Uppsala Hosp, PET Ctr, S-75185 Uppsala, Sweden. Pharmacia Biotech AB, S-75182Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2014-03-05

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