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A single carbocyclic nucleotide substitution in a 12mer DNA gives a Hoogsteen basepaired duplex (till 38 degrees C) and a hairpin (till 65 degrees C). A 600 MHZ NMR spectroscopic study.
Uppsala University.
Uppsala University.
Uppsala University.
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1999 (English)In: NUCLEOSIDES & NUCLEOTIDES, ISSN 0732-8311, Vol. 18, no 6-7, 1593-1596 p.Article in journal (Other scientific) Published
Abstract [en]

The impact of intramolecular stereoelectronic effects has been examined by comparison of the solution structures of natural oligo-DNA duplex, 5'((1)C(2)G(3)C(4)G(5)A(6)A(7)T(8)T(9)C(10)G(11)C(12)G)(2)(3'), and its carbocyclic-nucleotide analogues in which

Place, publisher, year, edition, pages
MARCEL DEKKER INC , 1999. Vol. 18, no 6-7, 1593-1596 p.
Identifiers
URN: urn:nbn:se:uu:diva-27409OAI: oai:DiVA.org:uu-27409DiVA: diva2:55304
Note
Addresses: Chattopadhyaya J, Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, Box 581, S-75123 Uppsala, Sweden. Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, S-75123 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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