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The solution conformation of a carbocyclic analog of the Dickerson-Drew dodecamer: Comparison with its own X-ray structure and that of the NMR structure of the native counterpart
Uppsala University.
Uppsala University.
Uppsala University.
Uppsala University.
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1998 (English)In: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ISSN 0739-1102, Vol. 16, no 3, 547-568 p.Article in journal (Other scientific) Published
Abstract [en]

The NMR conformation of a carbocyclic analog of the Dickerson-Drew dodecamer [d(CGCGAAT*T*'CGCG)](2) containing 6'-alpha-Me carbocyclic thymidines (T*) has been determined and compared with that of its X-ray structure. The solution structure of the 6'-alp

Place, publisher, year, edition, pages
ADENINE PRESS INC , 1998. Vol. 16, no 3, 547-568 p.
Keyword [en]
NUCLEIC-ACID FRAGMENTS; B-DNA DODECAMER; RESTRAINED MOLECULAR-DYNAMICS; 500-MHZ H-1-NMR SPECTROSCOPY; PROTON COUPLING-CONSTANTS; PSEUDOROTATIONAL EQUILIBRIUM; PENTOFURANOSE MOIETY; SUGAR CONFORMATION; KARPLUS EQUATION; C-NUCLEOSIDES
Identifiers
URN: urn:nbn:se:uu:diva-27417OAI: oai:DiVA.org:uu-27417DiVA: diva2:55312
Note
Addresses: Chattopadhyaya J, Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, Box 581, S-75123 Uppsala, Sweden. Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, S-75123 Uppsala, Sweden. Novartis Pharma Inc, Dept Oncol, CH-4002 Basel, Switzerland. Northwestern UAvailable from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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