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The residence time of the bound water in the hydrophobic minor groove of the carbocyclic-nucleoside analogs of Dickerson-Drew dodecamers
Uppsala University.
Uppsala University.
Uppsala University.
Uppsala University.
1998 (English)In: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ISSN 0739-1102, Vol. 16, no 3, 569-578 p.Article in journal (Other scientific) Published
Abstract [en]

The residence time of the bound water molecules in the antisense oligodeoxyribonucleotides containing 7'-alpha-methyl carbocyclic thymidines in duplex (I), d(5')((1)C(2)G(3)C(4)G(5)A(6)A(7)T(Mc)(8)T(Me)(9)C(10)G(11)C(12)G)(2)3', and 6'-alpha-hydroxy (T-OH

Place, publisher, year, edition, pages
ADENINE PRESS INC , 1998. Vol. 16, no 3, 569-578 p.
Keyword [en]
500-MHZ H-1-NMR SPECTROSCOPY; X-RAY CRYSTALLOGRAPHY; B-DNA DODECAMER; AQUEOUS-SOLUTION; PSEUDOROTATIONAL EQUILIBRIUM; SUGAR CONFORMATION; PENTOFURANOSE MOIETY; PROTEIN HYDRATION; NMR-SPECTROSCOPY; MOLECULES
Identifiers
URN: urn:nbn:se:uu:diva-27418OAI: oai:DiVA.org:uu-27418DiVA: diva2:55313
Note
Addresses: Chattopadhyaya J, Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, Box 581, S-75123 Uppsala, Sweden. Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, S-75123 Uppsala, Sweden. Novartis Pharma Inc, Dept Oncol, CH-4002 Basel, Switzerland. Northwestern UAvailable from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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